Definition of vicissitude
- change in circumstances, especially an unpleasant or unexpected change; often used in the plural (vicissitudes) to describe life’s ups and downs
Usage examples of vicissitude
The business survived many vicissitudes, including recessions, supply shortages, and sudden changes in demand.
After losing his job and then finding a better one, he learned to handle the vicissitudes of life.
Her memoir describes the vicissitudes of immigration: hope, loneliness, setbacks, and unexpected opportunities.